个人简介

王文生，男，博士，研究员，水稻分子设计技术与应用创新团队执行首席，博士生导师。主要从事水稻种质资源的基因组分析、抗逆相关基因的挖掘、功能验证及分子育种等工作。近年来，完成了3000份水稻核心种质资源遗传多样性和基因组变异解析工作，建立了水稻分子设计育种信息平台；开展了水稻核心种质和导入系抗逆表型的精准鉴定和基因型鉴定，利用多种组学手段挖掘了水稻抗逆有利基因，解析了水稻抗逆的分子调控机理和遗传网络。主持国家高层次人才特殊支持计划1项，国家自然科学基金项目2项，国家自然科学基金云南联合基金子课题1项，参加了重大国际农业合作、科技部支撑计划、863等多个项目。以第一或通讯作者在Nature、Nucleic Acids Research、Plant Biotechnology Journal、Journal ofExperimental Botany等刊物发表文章24篇，累计影响因子102.5。荣获国家高层次人才特殊支持计划“青年拔尖人才”、中国农学会青年科技奖和中国农业科学院“农科英才”。

研究方向

水稻种质资源的基因组分析、抗逆相关基因的挖掘、功能验证及分子育种

主要科研项目

1.  中共中央组织部人才支持项目；

2.  国家自然科学基金青年基金项目：水稻泛素化连接酶基因OsDRUP1的遗传多样性和抗旱分子机理解析；

3.  国家自然科学基金面上项目：嘌呤降解途径中尿囊素基因OsALN参与水稻耐盐的分子及生理机制研究。

代表性论文（著）

1.  Wensheng Wang#, Ramil Mauleon#, Zhiqiang Hu#, Dmytro Chebotarov#, Shuaishuai Tai#, Zhichao Wu#, Min Li#, Tianqing Zheng#, Roven Rommel Fuentes#, Fan Zhang#, Locedie Mansueto# et al. Genomic variation in 3,010 diverse accessions of Asian cultivated rice.Nature, 2018, 557: 43-49.

2.  Qiao Qin, Yinxiao Wang, Liyu Huang, Fengping Du, Xiuqin Zhao, Zhikang Li,Wensheng Wang* , Binying Fu*. A U-box E3 ubiquitin ligase OsPUB67 is positively involved in drought tolerance in rice.Plant Molecular Biology, 2020,102:89–107.

3.  Yinxiao Wang, Juan Wang， Xiuqin Zhao, Sheng Yang, Liyu Huang, Fengping Du, Zhikang Li,Xiangqiang Zhao, Binying Fu andWensheng Wang. Overexpression of the Transcription Factor Gene OsSTAP1 Increases Salt Tolerance inRice.Rice(2020) 13:50

4.  Wensheng Wang#, Xiuqin Zhao#, Min Li#, Liyu Huang, Jianlong Xu, FanZhang, Yanru Cui, Binying Fu*, Zhikang Li*. Complex molecular mechanisms underlying seedling salt tolerance in rice revealed by comparative transcriptome and metabolomic profiling.Journal of Experimental Botany, 2016, 67: 405-419.

5.  Zhiqiang Hu#,Wensheng Wang#, Zhichao Wu#, Chen Sun, Min Li, Jinyuan Lu, Binying Fu, Jianxin Shi, Jianlong Xu, Jue Ruan, Chaochun Wei*, Zhikang Li*. Novel sequences, structural variations and gene presence variations of Asian cultivated rice.Scientific Data, 2018, 5:180079.

6.  Wensheng Wang#, Qiao Qin#, Fan Sun, Yinxiao Wang, Dandan Xu, Zhikang Li and Binying Fu. Genome-Wide Differences in DNA Methylation Changes in Two Contrasting Rice Genotypes in Response to Drought Conditions.Frontiers in Plant Sciences, 2016 7:1675.

7.  Chunchao Wang#, Hong Yu#, Ji Huang#,WenSheng Wang#, Muhiuddin Faruquee, Fan Zhang XiuQin Zhao, BinYing Fu, Kai Chen, HongLiang Zhang, ShuaiShuai Tai, Chaochun Wei, Kenneth L. McNally Nickolai Alexandrov, XiuYing Gao, Jiayang Li ZhiKang Li, JianLong Xu, TianQing Zheng. Towards a deeper haplotype mining of complex traits in rice with RFGB v2.0.Plant Biotechnology Journal, 2020, 18(1):14-16.

8.  Wensheng Wang#，Binying Fu#，J Ali#， Jianlong Xu, Yongming Gao, Tianqing Zheng， Fan Zhang， Zhikang Li*. Genome-wide responses to selection and genetic networks underlying submergence tolerance in Rice (Oryza sativa L.)，Plant Genome, 2015, 8(2): 1-13.