个人简介

中国农业科学院作物科学研究所副研究员。2004在中国农业大学获得遗传学专业博士学位，2005-2007年在瑞典Lund 大学从事博士后工作，2007年进入中国农业科学院作物科学研究所工作至今。主要研究方向为玉米转基因与基因编辑、玉米籽粒发育分子机制解析。主持国家自然科学基金、生物育种课题、973任务等课题。以第一或通讯作者在Nucleic Acids Research, Plant Physiology, Journal Experimental Botany, Plant CellPhysiology等主流SCI期刊发表论文40余篇，获得第一发明人授权专利8项。

研究方向

玉米遗传转化机理解析、玉米基因编辑

主要科研项目

1. 国家自然基金“SMK11表观遗传调控玉米籽粒发育的分子机制”，起止时间2019.1-2022.12，经费60万元，主持人；

2. 转基因重大专项任务“玉米规模化转基因技术体系构建”，起止时间2011.1-2020.12，经费615万元，主持人；

3. 中国农科院所级统筹科研业务费“基于新型不育系的玉米杂交育种技术的建立”（S2018QY07），起止时间2018.1-2020.12，经费90万元，主持人；

4. 科技部973任务“玉米品质性状的全基因组遗传解析”，起止时间2014.1-2018.12，经费67万元，主持人；

5. 教育部留学人员基金“玉米锌指蛋白基因ZmSAP13的功能及作用机制研究”，起止时间2010.1-2010.10，经费4万元，主持人；

6. 转基因重大专项子课题“抗病虫、抗除草剂转基因玉米新品种培育”，起止时间2011.1-2020.12，经费3935.86万元，参加，主要执行人。

代表性论文

1.  Ren, Z., Fan, K., Fang, T., Zhang, J., Yang, L., Wang, J., Wang, G. and Liu, Y. (2019) Maize Empty Pericarp602 Encodes a P-Type PPR Protein That Is Essential for Seed Development.Plant & cell physiology60, 1734-1746.

2.  Du X, Fang T, Liu Y, Huang LY, Wang XL, Zhang J, Cui YB, Zang MS, Wang GY, Fu JJ,Liu YJ. Global Profiling of Alternative Splicing in Callus Induction of Immature Maize Embryo.In Vitro Cellular & Developmental Biology - Plant, 2019 https://doi.org/10.1007/s11627-019-10024-4.

3.  Du, X., Fang, T., Liu, Y., Huang, L., Zang, M., Wang, G., Liu, Y. and Fu, J. (2019) Transcriptome Profiling Predicts New Genes to Promote Maize Callus Formation and Transformation.Frontiers in plant science10, 1633.

4.  Chen, R., Xu, Q., Liu, Y., Zhang, J., Ren, D., Wang, G. and Liu, Y. (2018) Generation of Transgene-Free Maize Male Sterile Lines Using the CRISPR/Cas9 System.Frontiers in plant science9, 1180.

5.  Liu, Y., Zhang, Z., Fu, J., Wang, G., Wang, J. and Liu, Y. (2017) Transcriptome Analysis of Maize Immature Embryos Reveals the Roles of Cysteine in Improving Agrobacterium Infection Efficiency.Frontiers in plant science8, 1778.

6.  Kang D, Wang CY, Xu QL, Wang GY,Liu YJ. Characterization of maize male sterile 2 mutant by phenotypic and RNA sequencing analyses.Plant Breeding, (2017) 136, 319–330.

7.  Cao, Z., Zhang, W., Ning, X., Wang, B., Liu, Y. and Li, Q.X. (2017) Development of Monoclonal Antibodies Recognizing Linear Epitope: Illustration by Three Bacillus thuringiensis Crystal Proteins of Genetically Modified Cotton, Maize, and Tobacco.Journal of Agricultural and Food Chemistry65, 10115-10122.

8.  Zhang, Y., Zhang, W., Liu, Y., Wang, J., Wang, G. and Liu, Y. (2016) Development of monoclonal antibody-based sensitive ELISA for the determination of Cry1Ie protein in transgenic plant.Analytical and Bioanalytical Chemistry408, 8231-8239.

9.  Zhang YW, Liu Y, Zhang J, Wang CY, Wang JH, Liu YJ. Assessment of transgene copy number and zygosity of transgenic maize overexpressing Cry1Ie gene with SYBR® Green qRT-PCR.In Vitro Cell.Dev.Biol.—Plant(2015) 51:125–134.

10.  Yuan Y, Qi LJ, Yang J, Wu C,Liu YJ, Huang LQ. A Scutellariabaicalensis R2R3-MYB gene, SbMYB8, regulates flavonoid biosynthesis and improves drought stress tolerance in transgenic tobacco.Plant Cell Tiss Organ Cult(2015) 120:961–972.

11.  Ren ZJ, Liu Y, Kang D, Fan KJ, Wang CY, Wang GY,Liu YJ. Two alternative splicing variants of maize HKT1;1 confer salt tolerance in transgenic tobacco plants.Plant Cell Tiss Organ Cult(2015) 123:569–578.

12.  Ren ZJ, Cao GY, Zhang YW, Liu Y, Liu YJ(2015) Overexpression of a modified AM79 aroA gene in transgenic maize confers high tolerance to glyphosate.Journal of Integrative Agriculture, 414-422.

13.  Liu, Y., Cao, G., Chen, R., Zhang, S., Ren, Y., Lu, W., Wang, J. and Wang, G. (2015) Transgenic tobacco simultaneously overexpressing glyphosate N-acetyltransferase and 5-enolpyruvylshikimate-3-phosphate synthase are more resistant to glyphosate than those containing one gene.Transgenic Research24, 753-763.

14.  Liu YJ, Zhang YW, Liu Y, Lu W, Wang GY. Metabolic effects of glyphosate on transgenic maize expressing a G2-EPSPS gene from Pseudomonas fluorescens.J. Plant Biochem. Biotechnol.(2015) 24(2):233–241.

15.  Zhang YW,Liu YJ, Ren Y, Liu Y, Liang GM, Song FP, Bai SX, Wang JH, Wang GY. Overexpression of a novel Cry1Ie gene confers resistance to Cry1Ac-resistant cotton bollworm in transgenic lines of maize.Plant Cell Tiss Organ Cult(2013) 115:151–158.

16.  Zhang SX, Lian Y, Liu Y, Wang XQ,Liu YJ, Wang GY. Characterization of a Maize Wip1 Promoter in Transgenic Plants.Int. J. Mol. Sci.2013, 14, 23872-23892.

17.  Yuan Y, Wu C, Liu Y, Yang J, Huang L (2013) The Scutellariabaicalensis R2R3-MYB Transcription Factors Modulates Flavonoid Biosynthesis by Regulating GA Metabolism in Transgenic Tobacco Plants.PLoS ONE8(10): e77275.

18.  Yuan Y,Liu Y, Wu C, Chen S, Wang Z, Yang Z, Qin SS, Huang LQ (2012) Water Deficit Affected Flavonoid Accumulation by Regulating Hormone Metabolism in Scutellariabaicalensis Georgi Roots.PLoS ONE7(10): e42946.

19.  Liu YJ, Yuan Y, Liu YY, Liu Y, Fu JJ, Zheng J, Wang GY. Gene families of maize glutathione–ascorbate redox cycle respond differently to abiotic stresses.Journal of Plant Physiology169 (2012) 183– 192.

20.  Cao G,Liu Y, Zhang S, Yang X, Chen R, et al. (2012) A Novel 5-Enolpyruvylshikimate-3-Phosphate Synthase Shows High Glyphosate Tolerance in Escherichia coli and Tobacco Plants.PLoS ONE7(6): e38718.

21.  Liu, Y.J., Nunes-Nesi, A., Wallstrom, S.V., Lager, I., Michalecka, A.M., Norberg, F.E., Widell, S., Fredlund, K.M., Fernie, A.R. and Rasmusson, A.G. (2009) A redox-mediated modulation of stem bolting in transgenic Nicotiana sylvestris differentially expressing the external mitochondrial NADPH dehydrogenase.Plant Physiology150, 1248-1259.

22.  Liu, Y.J., Norberg, F.E., Szilagyi, A., De Paepe, R., Akerlund, H.E. and Rasmusson, A.G. (2008) The mitochondrial external NADPH dehydrogenase modulates the leaf NADPH/NADP+ ratio in transgenic Nicotiana sylvestris.Plant & Cell Physiology49, 251-263.